Chronic kidney disease represents a serious health problem which can lead to progressive loss of kidney function and eventually to end-stage renal disease. In many studies high sensitivity C-reactive protein (hsCRP) has been found as a sensitive marker of low-grade systemic inflammation. Recent studies suggest that patients with CKD suffer from inflammation which deteriorate progressively with increasing levels of renal failure. This study aims to evaluate the association between serum hs-CRP levels and chronic kidney disease in patients with T2DM patients. A significant positive correlation was found between hs-CRP levels with Serum Creatinine and significant negative correlation with eGFR. The study also revealed that, higher hsCRP was significantly associated with increasing the stage of CKD.

In conclusion, the outcome of this study suggests that elevated level of hsCRP can be used as a predictive factor of progression of CKD and management guideline in clinical aspects.

To be Updated