Cancer in pregnancy is an uncommon incidence, accounting for around 0.07-0.1% of all malignant tumors. Cervical cancer is the most common gynecological cancer during pregnancy. Glassy cell carcinoma (GCC) is a rare histological form of mixed adenosquamous cervical cancer that is highly aggressive and generally has a poor prognosis. We present the case of a 38-year-old woman whose routine cytology revealed a high grade squamous intraepithelial lesion (HSIL). A colposcopy-guided cervical punch biopsy was performed, revealing a histopathologic result of glassy cell carcinoma of the cervix, Stage 1B1. The management of GCC remains challenging, but a consensus has been reached through different services. The patient underwent neoadjuvant chemotherapy (NACT), delivered via classical cesarean section at 36th weeks age of gestation, and underwent radical hysterectomy with bilateral salpingo-oophorectomy and bilateral pelvic lymph node dissection one month postpartum, confirming the presence of glassy cell carcinoma.

Gimaica Ramos is from Sanchez Mira, Cagayan, Philippines, where her family’s emphasis on education instilled in her a drive for academic excellence. This passion led her to pursue a Bachelor of Science in Medical Technology at Far Eastern University in Manila. After working as a medical technologist for six months, she felt a deeper calling toward patient care, which inspired her to pursue a Doctor of Medicine at Far Eastern University Nicanor Reyes Medical Foundation and Medical Center. Her interest in obstetrics and gynecology developed early in medical school, and it has shaped my career path since. Currently, she serve as a Medical Officer III at Mariano Marcos Memorial Hospital and Medical Center, where she is undergoing her residency in Obstetrics and Gynecology. In her role, she have the privilege of working closely with women throughout all stages of life, providing care and support during some of their most challenging and rewarding moments.