Background: Gestational diabetes mellitus (GDM) represents a significant health challenge affecting pregnant women worldwide, impacting not only metabolic parameters but also psychological well-being and daily functioning. Understanding quality of life in this population is essential for comprehensive maternal care.

Objective: To assess the quality of life and identify associated factors among pregnant women diagnosed with gestational diabetes at the Gynecology-Obstetrics Department of Hedi Chaker University Hospital in Sfax, Tunisia.

Methods: A descriptive, cross-sectional, single-center study was conducted over four months (January-April 2025) involving 80 pregnant women with GDM. Data were collected through structured face-to-face interviews using a comprehensive questionnaire comprising sociodemographic characteristics, pregnancy-related information, diabetes management details, and the validated GDMQ-36 (Gestational Diabetes Mellitus Quality of Life Questionnaire). Quality of life scores were standardized on a 0-100 scale, with higher scores indicating better quality of life.

Results: The median quality of life score was 61.67 (IQR: 50-75), with 33.7% of participants reporting moderate quality of life. Analysis across five domains revealed variable impacts: medication and treatment showed the highest scores (median: 68), while social support demonstrated the lowest (median: 46.67). Significant associations were identified between poor quality of life and primiparity (OR=5.727, p=0.003) and eighth-month gestational age (OR=3.253, p=0.012). Notably, 73.8% of women reported difficulties adhering to dietary restrictions, and 63.7% struggled with physical activity requirements. Psychological concerns were prominent, with 42.5% expressing worry about fetal death and 43.8% feeling depressed.

Conclusion: Gestational diabetes substantially impacts multiple dimensions of women's quality of life, particularly regarding social support and high-risk pregnancy concerns. These findings underscore the need for holistic, patient-centered care approaches that address not only glycemic control but also psychological support, dietary counseling, and social resources to improve maternal well-being during this critical period.

Fedi Ben Dhaou is a distinguished educator and researcher at the Higher Institute of Nursing Sciences of Sfax, Tunisia, where he dedicates his expertise to shaping the next generation of healthcare professionals. Currently pursuing his PhD in Health Sciences with a specialization in Public Health, Fedi brings a unique multidisciplinary perspective to his academic work. His educational journey reflects a commitment to continuous professional development, holding a Master's degree in Health Sciences and a Professional Master's in Healthcare and Health Services Management. Fedi's clinical foundation was established through his work as an anesthesia nurse, providing him with invaluable frontline healthcare experience that informs his teaching and research. Demonstrating his dedication to both international scholarship and innovative pedagogical approaches, Fedi has earned specialized certifications in Health Science English and advanced training in Health Simulation. These credentials enhance his ability to deliver evidence-based, internationally-informed education while utilizing cutting-edge simulation techniques. His diverse background—spanning clinical practice, healthcare management, public health research, and medical education—positions him as a versatile scholar capable of bridging theory and practice. Through his teaching, research, and ongoing doctoral studies, Fedi Ben Dhaou continues to contribute meaningfully to advancing nursing education and public health initiatives in Tunisia and beyond.